Increased sporulation underpins adaptation of Clostridium difficile strain 630 to a biologically–relevant faecal environment, with implications for pathogenicity

Clostridium difficile virulence is driven primarily by the processes of toxinogenesis and sporulation, however many in vitro experimental systems for studying C. difficile physiology have arguably limited relevance to the human colonic environment. We therefore created a more physiologically–relevan...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Ternan, Nigel George, Moore, Nicola Diana, Smyth, Deborah, McDougall, Gordon James, Allwood, James William, Verrall, Susan, Gill, Christopher Ian Richard, Dooley, James Stephen Gerard, McMullan, Geoff
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232153/
https://ncbi.nlm.nih.gov/pubmed/30420658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35050-x
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