Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability

Clostridium difficile infection is a growing problem in healthcare settings worldwide and results in a considerable socioeconomic impact. New hypervirulent strains and acquisition of antibiotic resistance exacerbates pathogenesis; however, the survival strategy of C. difficile in the challenging gut...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jain, Shailesh, Smyth, Deborah, O’Hagan, Barry M. G., Heap, John T., McMullan, Geoff, Minton, Nigel P., Ternan, Nigel G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727486/
https://ncbi.nlm.nih.gov/pubmed/29235503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17583-9
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