Pathway-based subnetworks enable cross-disease biomarker discovery

Biomarkers lie at the heart of precision medicine. Surprisingly, while rapid genomic profiling is becoming ubiquitous, the development of biomarkers usually involves the application of bespoke techniques that cannot be directly applied to other datasets. There is an urgent need for a systematic meth...

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Pubblicato in:Nat Commun
Autori principali: Haider, Syed, Yao, Cindy Q., Sabine, Vicky S., Grzadkowski, Michal, Stimper, Vincent, Starmans, Maud H. W., Wang, Jianxin, Nguyen, Francis, Moon, Nathalie C., Lin, Xihui, Drake, Camilla, Crozier, Cheryl A., Brookes, Cassandra L., van de Velde, Cornelis J. H., Hasenburg, Annette, Kieback, Dirk G., Markopoulos, Christos J., Dirix, Luc Y., Seynaeve, Caroline, Rea, Daniel W., Kasprzyk, Arek, Lambin, Philippe, Lio’, Pietro, Bartlett, John M. S., Boutros, Paul C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232113/
https://ncbi.nlm.nih.gov/pubmed/30420699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07021-3
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