Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape

In most well-studied rod-shaped bacteria, peptidoglycan is primarily crosslinked by penicillin-binding proteins (PBPs). However, in mycobacteria, crosslinks formed by L,D-transpeptidases (LDTs) are highly abundant. To elucidate the role of these unusual crosslinks, we characterized Mycobacterium sme...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Baranowski, Catherine, Welsh, Michael A, Sham, Lok-To, Eskandarian, Haig A, Lim, Hoong Chuin, Kieser, Karen J, Wagner, Jeffrey C, McKinney, John D, Fantner, Georg E, Ioerger, Thomas R, Walker, Suzanne, Bernhardt, Thomas G, Rubin, Eric J, Rego, E Hesper
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2018
Fag:
Microbiology and Infectious Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231781/
https://ncbi.nlm.nih.gov/pubmed/30324906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37516
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