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High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production

Collagen overproduction is a feature of fibrosis and cancer, while insufficient deposition of functional collagen molecules and/or the secretion of malformed collagen are common in genetic disorders like osteogenesis imperfecta. Collagen secretion is an appealing therapeutic target in these and othe...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Wong, Madeline Y., Doan, Ngoc Duc, DiChiara, Andrew S., Papa, Louis J., Cheah, Jaime H., Soule, Christian K., Watson, Nicki, Hulleman, John D., Shoulders, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231715/
https://ncbi.nlm.nih.gov/pubmed/29676157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00378
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