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Benchtop Immobilized Metal Affinity Chromatography, Reconstitution and Assay of a Polyhistidine Tagged Metalloenzyme for the Undergraduate Laboratory

Benchtop immobilized metal affinity chromatography (IMAC), of polyhistidine tagged proteins is easily mastered by undergraduate students and has become the most widely used protein purification method in the modern literature. But, the application of affinity chromatography to metal binding proteins...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Colabroy, Keri L, Mayer, Katlyn
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231711/
https://ncbi.nlm.nih.gov/pubmed/30199034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58012
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