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Benchtop Immobilized Metal Affinity Chromatography, Reconstitution and Assay of a Polyhistidine Tagged Metalloenzyme for the Undergraduate Laboratory

Benchtop immobilized metal affinity chromatography (IMAC), of polyhistidine tagged proteins is easily mastered by undergraduate students and has become the most widely used protein purification method in the modern literature. But, the application of affinity chromatography to metal binding proteins...

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Sonraí Bibleagrafaíochta
Foilsithe in:J Vis Exp
Main Authors: Colabroy, Keri L, Mayer, Katlyn
Formáid: Artigo
Teanga:Inglês
Foilsithe: MyJove Corporation 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231711/
https://ncbi.nlm.nih.gov/pubmed/30199034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58012
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