pH-triggered charge-reversal and redox-sensitive drug-release polymer micelles codeliver doxorubicin and triptolide for prostate tumor therapy

AIM: To significantly promote cancer cell uptake and to achieve combination therapy and on-demand drug release, a pH-triggered charge-switchable and redox-responsive drug-release nanovehicle was developed in this study. MATERIALS AND METHODS: The nanocarrier was constructed by conjugating 3,3′-dithi...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Main Authors: Xu, Chen, Song, Ri-jin, Lu, Pei, Chen, Jian-chun, Zhou, Yong-qiang, Shen, Gang, Jiang, Min-jun, Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2018
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231516/
https://ncbi.nlm.nih.gov/pubmed/30510415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S182197
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