The α(2)δ-like Protein Cachd1 Increases N-type Calcium Currents and Cell Surface Expression and Competes with α(2)δ-1

Voltage-gated calcium channel auxiliary α2δ subunits are important for channel trafficking and function. Here, we compare the effects of α2δ-1 and an α2δ-like protein called Cachd1 on neuronal N-type (Ca(V)2.2) channels, which are important in neurotransmission. Previous structural studies show the...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Dahimene, Shehrazade, Page, Karen M., Kadurin, Ivan, Ferron, Laurent, Ho, Dominique Y., Powell, Gareth T., Pratt, Wendy S., Wilson, Stephen W., Dolphin, Annette C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231325/
https://ncbi.nlm.nih.gov/pubmed/30404013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.033
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