Attenuation of CD47-SIRPα Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis()()

The involvement of chronic inflammation in cholangiocarcinoma (CCA) progression is well established. Cluster of differentiation 47 (CD47) is mutually expressed in various cancers and serves as a protective signal for phagocytic elimination. CD47 signaling blockage is a recent treatment strategy; how...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Vaeteewoottacharn, Kulthida, Kariya, Ryusho, Pothipan, Phattarin, Fujikawa, Sawako, Pairojkul, Chawalit, Waraasawapati, Sakda, Kuwahara, Kazuhiko, Wongkham, Chaisiri, Wongkham, Sopit, Okada, Seiji
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
Assuntos:
Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231245/
https://ncbi.nlm.nih.gov/pubmed/30415063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.10.007
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