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2-Aminoadipic Acid–C(O)–Glutamate Based Prostate-Specific Membrane Antigen Ligands for Potential Use as Theranostics

[Image: see text] The design and synthesis of prostate specific membrane antigen (PSMA) ligands derived from 2-aminoadipic acid, a building block that has not previously been used to construct PSMA ligands, are reported. The effects of both the linker length and of an N-substituent of our PSMA ligan...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Nakajima, Ryo, Nováková, Zora, Tueckmantel, Werner, Motlová, Lucia, Bařinka, Cyril, Kozikowski, Alan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231180/
https://ncbi.nlm.nih.gov/pubmed/30429952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00318
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