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Iloprost attenuates hyperoxia-mediated impairment of lung development in newborn mice

Cyclooxygenase-2 (COX-2/PTGS2) mediates hyperoxia-induced impairment of lung development in newborn animals and is increased in the lungs of human infants with bronchopulmonary dysplasia (BPD). COX-2 catalyzes the production of cytoprotective prostaglandins, such as prostacyclin (PGI(2)), as well as...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Olave, Nelida, Lal, Charitharth Vivek, Halloran, Brian, Bhandari, Vineet, Ambalavanan, Namasivayam
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230878/
https://ncbi.nlm.nih.gov/pubmed/29952221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00125.2017
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