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Supraphysiological Levels of Oxygen Exposure During the Neonatal Period Impairs Signaling Pathways Required for Learning and Memory

Preterm infants often require prolonged oxygen supplementation and are at high risk of neurodevelopmental impairment. We recently reported that adult mice exposed to neonatal hyperoxia (postnatal day [P] 2 to 14) had spatial navigation memory deficits associated with hippocampal shrinkage. The mecha...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ramani, Manimaran, Kumar, Ranjit, Halloran, Brian, Lal, Charitharth Vivek, Ambalavanan, Namasivayam, McMahon, Lori L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028393/
https://ncbi.nlm.nih.gov/pubmed/29967535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28220-4
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