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The Role of NLRP3 and IL-1β in the Pathogenesis of Inflammatory Bowel Disease

It is logical to assume that a major pro-inflammatory mechanism, i.e., the NLRP3 inflammasome would play a prominent role in the pathogenesis of the Inflammatory Bowel Disease (IBD) in humans. However, while both studies of murine models of gut disease and patients provide data that the main cytokin...

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Vydáno v:Front Immunol
Hlavní autoři: Mao, Liming, Kitani, Atsushi, Strober, Warren, Fuss, Ivan J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230716/
https://ncbi.nlm.nih.gov/pubmed/30455704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02566
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