Myeloid-specific deletion of Zfp36 protects against insulin resistance and fatty liver in diet-induced obese mice

Obesity is associated with adipose tissue inflammation that contributes to insulin resistance. Zinc finger protein 36 (Zfp36) is an mRNA-binding protein that reduces inflammation by binding to cytokine transcripts and promoting their degradation. We hypothesized that myeloid-specific deficiency of Z...

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Vydáno v:Am J Physiol Endocrinol Metab
Hlavní autoři: Caracciolo, Valentina, Young, Jeanette, Gonzales, Donna, Ni, Yingchun, Flowers, Stephen J., Summer, Ross, Waldman, Scott A., Kim, Jason K., Jung, Dae Young, Noh, Hye Lim, Kim, Taekyoon, Blackshear, Perry J., O'Connell, Danielle, Bauer, Robert C., Kallen, Caleb B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230714/
https://ncbi.nlm.nih.gov/pubmed/29509432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00224.2017
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