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Myeloid-specific deletion of Zfp36 protects against insulin resistance and fatty liver in diet-induced obese mice
Obesity is associated with adipose tissue inflammation that contributes to insulin resistance. Zinc finger protein 36 (Zfp36) is an mRNA-binding protein that reduces inflammation by binding to cytokine transcripts and promoting their degradation. We hypothesized that myeloid-specific deficiency of Z...
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發表在: | Am J Physiol Endocrinol Metab |
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Main Authors: | , , , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
American Physiological Society
2018
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6230714/ https://ncbi.nlm.nih.gov/pubmed/29509432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00224.2017 |
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