Mature enteroendocrine cells contribute to basal and pathological stem cell dynamics in the small intestine

Lgr5-expressing intestinal stem cells (ISCs) maintain continuous and rapid generation of the intestinal epithelium. Here, we present evidence that dedifferentiation of committed enteroendocrine cells (EECs) contributes to maintenance of the epithelium under both basal conditions and in response to i...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Sei, Yoshitatsu, Feng, Jianying, Samsel, Leigh, White, Ayla, Zhao, Xilin, Yun, Sajung, Citrin, Deborah, McCoy, J. Philip, Sundaresan, Sinju, Hayes, Michael M., Merchant, Juanita L., Leiter, Andrew, Wank, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230697/
https://ncbi.nlm.nih.gov/pubmed/29848020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00036.2018
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