Mature enteroendocrine cells contribute to basal and pathological stem cell dynamics in the small intestine

Lgr5-expressing intestinal stem cells (ISCs) maintain continuous and rapid generation of the intestinal epithelium. Here, we present evidence that dedifferentiation of committed enteroendocrine cells (EECs) contributes to maintenance of the epithelium under both basal conditions and in response to i...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Gastrointest Liver Physiol
Asıl Yazarlar: Sei, Yoshitatsu, Feng, Jianying, Samsel, Leigh, White, Ayla, Zhao, Xilin, Yun, Sajung, Citrin, Deborah, McCoy, J. Philip, Sundaresan, Sinju, Hayes, Michael M., Merchant, Juanita L., Leiter, Andrew, Wank, Stephen A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230697/
https://ncbi.nlm.nih.gov/pubmed/29848020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00036.2018
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