TRPV4 Inhibition Improved Myelination and Reduced Glia Reactivity and Inflammation in a Cuprizone-Induced Mouse Model of Demyelination

The inhibition of demyelination and the promotion of remyelination are both considerable challenges in the therapeutic process for many central nervous system (CNS) diseases. Increasing evidence has demonstrated that neuroglial activation and neuroinflammation are responsible for myelin sheath damag...

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Détails bibliographiques
Publié dans:Front Cell Neurosci
Auteurs principaux: Liu, Meiying, Liu, Xuan, Wang, Lei, Wang, Yu, Dong, Fuxing, Wu, Jian, Qu, Xuebin, Liu, Yanan, Liu, Zhian, Fan, Hongbin, Yao, Ruiqin
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230558/
https://ncbi.nlm.nih.gov/pubmed/30455633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00392
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