TRPV4 Inhibition Improved Myelination and Reduced Glia Reactivity and Inflammation in a Cuprizone-Induced Mouse Model of Demyelination

The inhibition of demyelination and the promotion of remyelination are both considerable challenges in the therapeutic process for many central nervous system (CNS) diseases. Increasing evidence has demonstrated that neuroglial activation and neuroinflammation are responsible for myelin sheath damag...

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Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Liu, Meiying, Liu, Xuan, Wang, Lei, Wang, Yu, Dong, Fuxing, Wu, Jian, Qu, Xuebin, Liu, Yanan, Liu, Zhian, Fan, Hongbin, Yao, Ruiqin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230558/
https://ncbi.nlm.nih.gov/pubmed/30455633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00392
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