Simvastatin attenuates tibial bone loss in rats with type 1 diabetes and periodontitis

BACKGROUND: Diabetes induces long bone loss and aggravation of periodontitis-induced alveolar bone loss. Simvastatin (SIM), which is a lipid-lowering agent is known to have an anabolic effect on bone. Therefore, we investigated effect of SIM on tibial and alveolar bone loss in type 1 diabetic rats w...

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Pubblicato in:J Transl Med
Autori principali: Kim, Ae Ri, Kim, Ji-Hye, Kim, Aeryun, Sohn, Yongsung, Cha, Jeong-Heon, Bak, Eun-Jung, Yoo, Yun-Jung
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230277/
https://ncbi.nlm.nih.gov/pubmed/30413166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1681-6
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