Tumor necrosis factor-α antagonist diminishes osteocytic RANKL and sclerostin expression in diabetes rats with periodontitis

Type 1 diabetes with periodontitis shows elevated TNF-α expression. Tumor necrosis factor (TNF)-α stimulates the expression of receptor activator of nuclear factor-κB ligand (RANKL) and sclerostin. The objective of this study was to determine the effect of TNF-α expression of osteocytic RANKL and sc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Ji-Hye, Kim, Ae Ri, Choi, Yun Hui, Jang, Sungil, Woo, Gye-Hyeong, Cha, Jeong-Heon, Bak, Eun-Jung, Yoo, Yun-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730195/
https://ncbi.nlm.nih.gov/pubmed/29240821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189702
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