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Partial reduction of microglia does not affect tau pathology in aged mice

BACKGROUND: Activation of inflammation pathways in the brain occurs in Alzheimer’s disease and may contribute to the accumulation and spread of pathological proteins including tau. The goal of this study was to identify how changes in microglia, a key inflammatory cell type, may contribute to tau pr...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Bennett, Rachel E., Bryant, Annie, Hu, Miwei, Robbins, Ashley B., Hopp, Sarah C., Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230271/
https://ncbi.nlm.nih.gov/pubmed/30413160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1348-5
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