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INDY REDUCTION PRESERVES INTESTINAL STEM CELL HOMEOSTASIS
Indy (I’m not dead yet) encodes the fly homolog of a mammalian mIndy (SLC13A5) plasma membrane citrate transporter. Reduction of Indy gene activity in flies, or its homolog in worms extends longevity. Decreased expression of INDY in flies, worms, rats, and mice has beneficial effects on energy balan...
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| Gepubliceerd in: | Innov Aging |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6230115/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.339 |
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