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MOLECULAR MECHANISMS OF LIFESPAN EXTENSION IN YEAST WITH IMPAIRED RIBOSOME RECYCLING

Previous studies have identified hundreds of genes whose deletion extends replicative lifespan (RLS) of Saccharomyces cerevisiae. Among gene deletions that lead to RLS extension, a recent genome-wide analysis uncovered two genes, DOM34 and HBS1, encoding factors involved in recycling of terminating...

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Publicado en:Innov Aging
Autores principales: Areshkov, P, Beaupere, C, Labunskyy, V
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6229856/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.379
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