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IMPAIRMENT OF AN ENDOTHELIAL NAD+-H2S SIGNALING NETWORK IS A REVERSIBLE CAUSE OF VASCULAR AGING

With aging there is a notable decline in capillary density and blood flow contributing to mortality and morbidity. The use of NAD+ boosters to reverse aspects of aging, is in part, through the mechanism of activating sirtuin deacylases (SIRT1–SIRT7) that mediate the benefits of exercise and calorie...

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Bibliografske podrobnosti
izdano v:Innov Aging
Main Authors: Bonkowski, M S, Das, A, Schultz, M B, Lu, Y, Mitchell, J, Wu, L, Guarente, L, Sinclair, D A
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6229163/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.2966
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