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IMPAIRMENT OF AN ENDOTHELIAL NAD+-H2S SIGNALING NETWORK IS A REVERSIBLE CAUSE OF VASCULAR AGING
With aging there is a notable decline in capillary density and blood flow contributing to mortality and morbidity. The use of NAD+ boosters to reverse aspects of aging, is in part, through the mechanism of activating sirtuin deacylases (SIRT1–SIRT7) that mediate the benefits of exercise and calorie...
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| Publicado no: | Innov Aging |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6227600/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.1446 |
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