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TARGETING GROWTH FACTOR SIGNALING TO DELAY AGING
Diminished growth hormone/ insulin–like growth factor-1 (GH/IGF-1) signaling extends lifespan. In humans, low IGF-1 is also linked to less cancer risk while mutations associated with less GH/IGF-1 signaling are enriched in centenarians. Paradoxically, low IGF-1 in humans is associated with increased...
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| Veröffentlicht in: | Innov Aging |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6228352/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.278 |
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