Загрузка...
NEW INSIGHTS INTO THE PROTEASOME FUNCTION AND DEGRADATION OF MISFOLDED PROTEINS
Protein degradation by the UPS is controlled through ubiquitin conjugation and control of proteasome activity. Most 26S proteasomes are in a latent state, but bindings of ubiquitinated proteins enhance its capacity to hydrolyze substrates and stimulates binding of key cofactors. Proteasome function...
Сохранить в:
| Опубликовано в: : | Innov Aging |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2018
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6228170/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.1443 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|