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CIRCULATING CELL-FREE APOPTOTIC MITOCHONDRIAL DNA FRAGMENTS IN FRAIL OLD ADULTS
In older adults, cellular senescence is linked to frailty and risk of death. Senescent cells accumulate dysfunctional mitochondria. With cell turnover, mtDNA fragments are released into circulation. These fragments can be utilized as biomarker for cell turnover and to distinguish apoptotic vs necrot...
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| Publié dans: | Innov Aging |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6227557/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.229 |
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