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Circulating cell-free mitochondrial DNA, but not leukocyte mitochondrial DNA copy number, is elevated in major depressive disorder

Major depressive disorder (MDD) has been linked to mitochondrial defects, which could manifest in mitochondrial DNA (mtDNA) polymorphisms or mutations. Additionally, copy number of mtDNA (mtDNA-cn) can be quantified in peripheral blood mononuclear cells (PBMC)s, indirectly reflecting cellular energe...

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Bibliografski detalji
Izdano u:Neuropsychopharmacology
Glavni autori: Lindqvist, Daniel, Wolkowitz, Owen M., Picard, Martin, Ohlsson, Lars, Bersani, Francesco S., Fernström, Johan, Westrin, Åsa, Hough, Christina M., Lin, Jue, Reus, Victor I., Epel, Elissa S., Mellon, Synthia H.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983469/
https://ncbi.nlm.nih.gov/pubmed/29453441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-017-0001-9
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