Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. Mesangial cell (MC) loss is correlated with worsening renal function in DN. Disturbance of angiopoietin (Angpt)/Tie ligand-receptor system causes inflammation and abnormal angiogenesis. This association between elevated circu...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Tsai, Yi-Chun, Kuo, Po-Lin, Hung, Wei-Wen, Wu, Ling-Yu, Wu, Ping-Hsun, Chang, Wei-An, Kuo, Mei-Chuan, Hsu, Ya-Ling
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226567/
https://ncbi.nlm.nih.gov/pubmed/30414568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.10.003
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