Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases

In silico quantification of cell proportions from mixed-cell transcriptomics data (deconvolution) requires a reference expression matrix, called basis matrix. We hypothesize that matrices created using only healthy samples from a single microarray platform would introduce biological and technical bi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Vallania, Francesco, Tam, Andrew, Lofgren, Shane, Schaffert, Steven, Azad, Tej D., Bongen, Erika, Haynes, Winston, Alsup, Meia, Alonso, Michael, Davis, Mark, Engleman, Edgar, Khatri, Purvesh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226523/
https://ncbi.nlm.nih.gov/pubmed/30413720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07242-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados