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Diffusion-limited association of disordered protein by non-native electrostatic interactions

Intrinsically disordered proteins (IDPs) usually fold during binding to target proteins. In contrast to interactions between folded proteins, this additional folding step makes the binding process more complex. Understanding the mechanism of coupled binding and folding of IDPs requires analysis of b...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kim, Jae-Yeol, Meng, Fanjie, Yoo, Janghyun, Chung, Hoi Sung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226484/
https://ncbi.nlm.nih.gov/pubmed/30413699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06866-y
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