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Dehydroepiandrosterone (DHEA)-SO(4) Depot and Castration-Resistant Prostate Cancer
Dehydroepiandrosterone (DHEA)-SO(4) of adrenal origin is the major C19 steroid in the serum. It is a precursor of intratumoral androgen biosynthesis in patients with advanced prostate cancer following chemical or surgical castration. DHEA is a product of the P450c17 (17α-hydroxylase-17,20-lyase) enz...
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| Publicado no: | Vitam Horm |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6226251/ https://ncbi.nlm.nih.gov/pubmed/30029732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.vh.2018.01.007 |
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