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TiCl(4) Promoted Three Component Coupling Reaction : A New Method for the Synthesis of Functionalized Tetrahydrofurans and Tetrahydropyrans
TiC1(4) promoted coupling of ethyl glyoxylate and dihydrofuran or dihydropyran provided oxonium ion intermediates which upon reaction with a nucleophilic trapping agent such as allyltrimethylsilane provided 2,3-disubstituted tetrahydrofurans and pyrans in good yields. The overall protocol constitute...
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| Publicat a: | Tetrahedron Lett |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6226096/ https://ncbi.nlm.nih.gov/pubmed/30422132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0040-4039(98)02633-1 |
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