Enantioselective Ruthenium Catalyzed Benzocyclobutenone-Ketol Cycloaddition: Merging C-C Bond Activation and Transfer Hydrogenative Coupling for Type II Polyketide Construction

The first enantioselective intermolecular metal catalyzed cycloadditions of benzocyclobutenones via C-C bond oxidative addition are described. In the presence of a ruthenium(0) complex modified by (R)-DM-SEGPHOS, tetralone-derived ketols and benzocyclobutenones combine to form cycloadducts with comp...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Ambler, Brett R., Turnbull, Ben W. H., Suravarapu, Sankar Rao, Uteuliyev, Maulen M., Huynh, Nancy O., Krische, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226000/
https://ncbi.nlm.nih.gov/pubmed/29992811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b05724
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados