The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression

We found that the cancerous pancreas harbors a markedly more abundant microbiome compared to normal pancreas in both mice and humans, while select bacteria are differentially increased in the tumorous pancreas compared to gut. Ablation of the microbiome protects against pre-invasive and invasive PDA...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Discov
Egile Nagusiak: Pushalkar, Smruti, Hundeyin, Mautin, Daley, Donnele, Zambirinis, Constantinos P., Kurz, Emma, Mishra, Ankita, Mohan, Navyatha, Aykut, Berk, Usyk, Mykhaylo, Torres, Luisana E., Werba, Gregor, Zhang, Kevin, Guo, Yuqi, Li, Qianhao, Akkad, Neha, Lall, Sarah, Wadowski, Benjamin, Gutierrez, Johana, Rossi, Juan Andres Kochen, Herzog, Jeremy W., Diskin, Brian, Torres-Hernandez, Alejandro, Leinwand, Josh, Wang, Wei, Taunk, Pardeep S., Savadkar, Shivraj, Janal, Malvin, Saxena, Anjana, Li, Xin, Cohen, Deirdre, Sartor, R. Balfour, Saxena, Deepak, Miller, George
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225783/
https://ncbi.nlm.nih.gov/pubmed/29567829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-1134
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