Live imaging and tracking of genome regions in CRISPR/dCas9 knock-in mice

CRISPR/dCas9 is a versatile tool that can be used to recruit various effectors and fluorescent molecules to defined genome regions where it can modulate genetic and epigenetic markers, or track the chromatin dynamics in live cells. In vivo applications of CRISPR/dCas9 in animals have been challenged...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Duan, Jinzhi, Lu, Guangqing, Hong, Yu, Hu, Qingtao, Mai, Xueying, Guo, Jing, Si, Xiaofang, Wang, Fengchao, Zhang, Yu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225728/
https://ncbi.nlm.nih.gov/pubmed/30409154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1530-1
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