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Involvement of Up-Regulation of DR5 Expression and Down-Regulation of c-FLIP in Niclosamide-Mediated TRAIL Sensitization in Human Renal Carcinoma Caki Cells

Niclosamide is used to treat intestinal parasite infections, as being an anthelmintic drug. Recently, several papers suggest the niclosamide inhibits multiple signaling pathways, which are highly activated and mutated in cancer. Here, niclosamide was evaluated for identifying strategies to overcome...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Yun, Jeong Mi, Woo, Seon Min, Seo, Seung Un, Min, Kyoung-Jin, Kim, Dong Eun, Kwon, Taeg Kyu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225471/
https://ncbi.nlm.nih.gov/pubmed/30189637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092264
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