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Involvement of Up-Regulation of DR5 Expression and Down-Regulation of c-FLIP in Niclosamide-Mediated TRAIL Sensitization in Human Renal Carcinoma Caki Cells

Niclosamide is used to treat intestinal parasite infections, as being an anthelmintic drug. Recently, several papers suggest the niclosamide inhibits multiple signaling pathways, which are highly activated and mutated in cancer. Here, niclosamide was evaluated for identifying strategies to overcome...

詳細記述

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書誌詳細
出版年:Molecules
主要な著者: Yun, Jeong Mi, Woo, Seon Min, Seo, Seung Un, Min, Kyoung-Jin, Kim, Dong Eun, Kwon, Taeg Kyu
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225471/
https://ncbi.nlm.nih.gov/pubmed/30189637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092264
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