Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages

Heat shock cognate protein 70 (HSC70), a molecular chaperone, is constitutively expressed by mammalian cells to regulate various cellular functions. It is associated with many diseases and is a potential therapeutic target. Although HSC70 also possesses an anti-inflammatory action, the mechanism of...

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Publicado no:Molecules
Main Authors: Sulistyowati, Erna, Lee, Mei-Yueh, Wu, Lin-Chi, Hsu, Jong-Hau, Dai, Zen-Kong, Wu, Bin-Nan, Lin, Ming-Chung, Yeh, Jwu-Lai
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225271/
https://ncbi.nlm.nih.gov/pubmed/30142934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092124
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