TADAFER II: Tadalafil treatment for fetal growth restriction - a study protocol for a multicenter randomised controlled phase II trial

INTRODUCTION: There is no proven therapy to reverse or ameliorate fetal growth restriction (FGR). Sildenafil, a selective phosphodiesterase 5 (PDE5) inhibitor, has been reported to potentially play a therapeutic role in FGR, but this has not been established. Tadalafil is also a selective PDE5 inhib...

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Dades bibliogràfiques
Publicat a:BMJ Open
Autors principals: Umekawa, Takashi, Maki, Shintaro, Kubo, Michiko, Tanaka, Hiroaki, Nii, Masafumi, Tanaka, Kayo, Osato, Kazuhiro, Kamimoto, Yuki, Tamaru, Satoshi, Ogura, Toru, Nishimura, Yuki, Kodera, Mayumi, Minamide, Chisato, Nishikawa, Masakatsu, Endoh, Masayuki, Kimura, Tadashi, Kotani, Tomomi, Nakamura, Masamitsu, Sekizawa, Akihiko, Ikeda, Tomoaki
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2018
Matèries:
Obstetrics and Gynaecology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224767/
https://ncbi.nlm.nih.gov/pubmed/30381311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2017-020948
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