miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer

Epithelial ovarian carcinoma (EOC) is the most lethal gynecologic malignancy. However, the molecular mechanisms remain unclear. In this study, we found that miR-146b was downregulated in EOC and its expression level was negatively correlated with the pathological staging. Follow-up functional experi...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Yan, Meina, Yang, Xinxin, Shen, Rong, Wu, Chengjiang, Wang, Hui, Ye, Qing, Yang, Peifang, Zhang, Lubin, Chen, Miao, Wan, Bing, Zhang, Qinqin, Xia, Sheng, Lu, Xiaodong, Shao, Genbao, Zhou, Xiaoming, Yu, Jun, Shao, Qixiang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224598/
https://ncbi.nlm.nih.gov/pubmed/30409964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1093-9
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