miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer

Epithelial ovarian carcinoma (EOC) is the most lethal gynecologic malignancy. However, the molecular mechanisms remain unclear. In this study, we found that miR-146b was downregulated in EOC and its expression level was negatively correlated with the pathological staging. Follow-up functional experi...

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Vydáno v:Cell Death Dis
Hlavní autoři: Yan, Meina, Yang, Xinxin, Shen, Rong, Wu, Chengjiang, Wang, Hui, Ye, Qing, Yang, Peifang, Zhang, Lubin, Chen, Miao, Wan, Bing, Zhang, Qinqin, Xia, Sheng, Lu, Xiaodong, Shao, Genbao, Zhou, Xiaoming, Yu, Jun, Shao, Qixiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224598/
https://ncbi.nlm.nih.gov/pubmed/30409964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1093-9
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