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ZNF598 Is a Quality Control Sensor of Collided Ribosomes
Aberrantly slow translation elicits quality control pathways initiated by the ubiquitin ligase ZNF598. How ZNF598 discriminates physiologic from pathologic translation complexes and ubiquitinates stalled ribosomes selectively is unclear. Here, we find that the minimal unit engaged by ZNF598 is the c...
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| 出版年: | Mol Cell |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cell Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6224477/ https://ncbi.nlm.nih.gov/pubmed/30293783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.08.037 |
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