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Regenerative Approaches in Huntington’s Disease: From Mechanistic Insights to Therapeutic Protocols
Huntington’s Disease (HD) is a neurodegenerative disorder caused by a CAG expansion in the exon-1 of the IT15 gene encoding the protein Huntingtin. Expression of mutated Huntingtin in humans leads to dysfunction and ultimately degeneration of selected neuronal populations of the striatum and cerebra...
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| Veröffentlicht in: | Front Neurosci |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6224350/ https://ncbi.nlm.nih.gov/pubmed/30450032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00800 |
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