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Unraveling the enigma: elucidating the relationship between the physicochemical properties of aluminium-based adjuvants and their immunological mechanisms of action

Aluminium salts are by far the most commonly used adjuvants in vaccines. There are only two aluminium salts which are used in clinically-approved vaccines, Alhydrogel(®) and AdjuPhos(®), while the novel aluminium adjuvant used in Gardasil(®) is a sulphated version of the latter. We have investigated...

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Detalhes bibliográficos
Publicado no:Allergy Asthma Clin Immunol
Main Authors: Shardlow, Emma, Mold, Matthew, Exley, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223008/
https://ncbi.nlm.nih.gov/pubmed/30455719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13223-018-0305-2
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