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From Stock Bottle to Vaccine: Elucidating the Particle Size Distributions of Aluminum Adjuvants Using Dynamic Light Scattering

The physicochemical properties of aluminum salts are key determinants of their resultant adjuvanticity in vivo when administered as part of a vaccine. While there are links between particle size and the efficacy of the immune response, the limited literature directly characterizing the PSD of alumin...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Shardlow, Emma, Mold, Matthew, Exley, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220009/
https://ncbi.nlm.nih.gov/pubmed/28119911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2016.00048
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