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Synthesis, Molecular Docking and Anticancer Activity of Diflunisal Derivatives as Cyclooxygenase Enzyme Inhibitors

Cyclooxygenase enzymes play a vital role in inflammatory pathways in the human body. Apart from their relation with inflammation, the additional involvement of COX-2 enzyme with cancer activity was recently discovered. In some cancer types the level of COX-2 enzyme is increased indicating that this...

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Podrobná bibliografie
Vydáno v:Molecules
Hlavní autoři: Coşkun, Göknil Pelin, Djikic, Teodora, Hayal, Taha Bartu, Türkel, Nezaket, Yelekçi, Kemal, Şahin, Fikrettin, Küçükgüzel, Ş. Güniz
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222829/
https://ncbi.nlm.nih.gov/pubmed/30082676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23081969
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