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Synthesis and Anticancer and Antimicrobial Evaluation of Novel Ether-linked Derivatives of Ornidazole

OBJECTIVES: Some novel 1-(2-methyl-5-nitro-1H-imidazol-1-yl)-3-(substituted phenoxy)propan-2-ol derivatives (3a-g) were designed and synthesized. MATERIALS AND METHODS: Compounds 3a-g were obtained by refluxing ornidazole (1) with the corresponding phenolic compounds (2a-g) in the presence of anhydr...

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Detalhes bibliográficos
Publicado no:Turk J Pharm Sci
Main Authors: ŞENKARDEŞ, Sevil, KULABAŞ, Necla, BİNGÖL ÖZAKPINAR, Özlem, KALAYCI, Sadık, ŞAHİN, Fikrettin, KÜÇÜKGÜZEL, İlkay, KÜÇÜKGÜZEL, Ş. Güniz
Formato: Artigo
Idioma:Inglês
Publicado em: Galenos Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227874/
https://ncbi.nlm.nih.gov/pubmed/32454765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjps.galenos.2018.59389
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