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Synthesis and Cytoprotective Characterization of 8-Hydroxyquinoline Betti Products

The 8-hydroxyquinoline pharmacophore scaffold has been shown to possess a range of activities as metal chelation, enzyme inhibition, cytotoxicity, and cytoprotection. Based on our previous findings we set out to optimize the scaffold for cytoprotective activity for its potential application in centr...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kanizsai, Iván, Madácsi, Ramóna, Hackler Jr., László, Gyuris, Márió, Szebeni, Gábor J., Huzián, Orsolya, Puskás, László G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222637/
https://ncbi.nlm.nih.gov/pubmed/30072653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23081934
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