Synthesis of 8-Hydroxyquinoline Derivatives as Novel Antitumor Agents

[Image: see text] This letter describes the preparation of quinoline derivatives and their cytotoxic potentials toward human carcinoma cell lines. Among the selected compounds, 8-hydroxy-2-quinolinecarbaldehyde (3) showed the best in vitro cytotoxicity against the human cancer cell lines, including...

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Autori principali: Chan, Sau Hing, Chui, Chung Hin, Chan, Shun Wan, Kok, Stanton Hon Lun, Chan, Dessy, Tsoi, Miriam Yuen Tung, Leung, Polly Hang Mei, Lam, Alfred King Yin, Chan, Albert Sun Chi, Lam, Kim Hung, Tang, Johnny Cheuk On
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2012
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027363/
https://ncbi.nlm.nih.gov/pubmed/24900641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300238z
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