Novel 5′-Norcarbocyclic Derivatives of Bicyclic Pyrrolo- and Furano[2,3-d]Pyrimidine Nucleosides

Here we report the synthesis and biological activity of new 5′-norcarbocyclic derivatives of bicyclic pyrrolo- and furano[2,3-d]pyrimidines with different substituents in the heterocyclic ring. Lead compound 3i, containing 6-pentylphenyl substituent, displays inhibitory activity with respect to a nu...

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Publié dans:Molecules
Auteurs principaux: Klimenko, Anna A., Matyugina, Elena S., Logashenko, Evgeniya B., Solyev, Pavel N., Zenkova, Marina A., Kochetkov, Sergey N., Khandazhinskaya, Anastasia L.
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222425/
https://ncbi.nlm.nih.gov/pubmed/30332788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23102654
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